Serum anti-enteric neuronal antibodies in patients with achalasia and their association with clinical profiles

Table 6 Dose-response association between anti‐enteric neuronal antibody intensity levels and contents, anatomy, resistance, and stasis scores

Variable	β (95%CI)	P value
AENA intensity (per category increase)	0.43 (0.14-0.73)	0.005b
Age (per year)	-0.00 (-0.02 to 0.02)	0.990
Gender (male vs female)	0.12 (-0.44 to 0.68)	0.670
Disease duration (per year)	0.00 (-0.03 to 0.04)	0.802
Achalasia subtype	-0.04 (-0.62 to 0.54)	0.893

^bP < 0.01.

The model was adjusted for age, sex, disease duration, and achalasia subtype. Anti-enteric neuronal antibody intensity was analyzed as an ordinal variable (negative = 0; moderate-positive = 1; strong-positive = 2). AENA: Anti-enteric neuronal antibody; CI: Confidence interval.