Copyright: ©Author(s) 2026.
World J Gastroenterol. Sep 21, 2026; 32(35): 121494
Published online Sep 21, 2026. doi: 10.3748/wjg.121494
Published online Sep 21, 2026. doi: 10.3748/wjg.121494
Figure 3 Relationships between Tn antigen and podoplanin expression.
A: Expression characteristics of C1GALT1 and podoplanin (PDPN) in major cellular subsets; B and C: Spatial expression localization of C1GALT1 and PDPN in the single-cell landscape; D: Scatter plot of C1GALT1 vs PDPN expression; E: Mechanistic role of PDPN; F and G: Western blot analysis confirming reduced PDPN expression in Tn antigen-expressing. CMS: Consensus molecular subtype; PDPN: Podoplanin.
- Citation: Fan LW, Wu XZ, Liu ZW, Lin Q, Du JX, Tian YT, Dong XC, Xu DK. Tn antigen-driven downregulation of podoplanin promotes colorectal cancer invasion. World J Gastroenterol 2026; 32(35): 121494
- URL: https://www.wjgnet.com/1007-9327/full/v32/i35/121494.htm
- DOI: https://dx.doi.org/10.3748/wjg.121494