Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors

doi:10.3748/wjg.v32.i34.119567

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 14, 2026; 32(34): 119567
Published online Sep 14, 2026. doi: 10.3748/wjg.v32.i34.119567

Table 7 Multivariate Cox proportional hazards regression analysis of risk factors affecting progression-free survival in gastric cancer patients treated with immune checkpoint inhibitors

Parameters	P value	Hazard ratio	95%CI
Eastern Cooperative Oncology Group (2)	0.018	1.642	1.088-2.478
Clinical staging (IV)	0.001	2.149	1.361-3.394
Number of distant metastases (≥ 2)	0.032	1.593	1.042-2.435
Treatment regimen (combination therapy)	0.076	0.712	0.491-1.032
Programmed cell death ligand 1 overexpression (combined positive score ≥ 1)	0.124	0.803	0.608-1.061
High systemic immune-inflammation index (≥ 593.995)	0.005	1.896	1.214-2.961

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Citation: Guo R, Gao M. Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors. World J Gastroenterol 2026; 32(34): 119567
URL: https://www.wjgnet.com/1007-9327/full/v32/i34/119567.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i34.119567

Guo R, Gao M. Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors. World J Gastroenterol 2026; 32(34): 119567 [DOI: 10.3748/wjg.v32.i34.119567]

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