Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors

doi:10.3748/wjg.v32.i34.119567

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 14, 2026; 32(34): 119567
Published online Sep 14, 2026. doi: 10.3748/wjg.v32.i34.119567

Table 1 Comparison of baseline characteristics of gastric cancer patients in the poor prognosis and good prognosis groups, n (%)/mean ± SD

Parameters	Good prognosis group (n = 143)	Poor prognosis group (n = 95)	t/χ²	P value
Gender			0.163	0.687
Female	52 (36.36)	37 (38.95)
Male	91 (63.64)	58 (61.05)
Age (years)	62.34 ± 4.15	63.28 ± 3.87	1.756	0.080
Body mass index (kg/m²)	22.15 ± 3.02	21.89 ± 2.24	0.756	0.450
Eastern Cooperative Oncology Group			12.643	0.002
0	72 (50.35)	38 (40.00)
1	58 (40.56)	32 (33.68)
2	13 (9.09)	25 (26.32)
Clinical staging			10.659	0.001
IV	91 (63.64)	79 (83.16)
III	52 (36.36)	16 (16.84)
Number of distant metastases			8.636	0.003
≥ 2	61 (42.66)	59 (62.11)
< 2	82 (57.34)	36 (37.89)
Previous gastric cancer resection surgery			0.692	0.406
Yes	65 (45.45)	38 (40.00)
No	78 (54.55)	57 (60.00)
Treatment regimen			8.325	0.004
Combination therapy	83 (58.04)	37 (38.95)
Monotherapy	60 (41.96)	58 (61.05)
Programmed cell death ligand 1 overexpression (combined positive score)			8.692	0.003
≥ 1	80 (55.94)	71 (74.74)
< 1	63 (44.06)	24 (25.26)

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Citation: Guo R, Gao M. Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors. World J Gastroenterol 2026; 32(34): 119567
URL: https://www.wjgnet.com/1007-9327/full/v32/i34/119567.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i34.119567

Guo R, Gao M. Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors. World J Gastroenterol 2026; 32(34): 119567 [DOI: 10.3748/wjg.v32.i34.119567]

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