Development and validation of a tongue image-clinical nomogram for detection of advanced colorectal adenoma

Figure 8 Comparison of tongue-based models and conventional risk scores in the Asia-Pacific colorectal screening score ≥ 4 high-risk subgroup. A: Receiver operating characteristic (ROC) curves of the tongue image-clinical nomogram, tongue-only model, Asia-Pacific colorectal screening (APCS) score, and modified APCS score in the high-risk training cohort; B: ROC curves of the four approaches in the high-risk validation cohort; C: Decision curve analysis (DCA) in the high-risk training cohort, in which the all and none lines represent the treat-all and treat-none strategies, respectively; D: DCA in the high-risk validation cohort; E: Calibration curves in the high-risk training cohort; F: Calibration curves in the high-risk validation cohort. APCS: Asia-Pacific colorectal screening; M-APCS: Modified Asia-Pacific colorectal screening; AUC: Area under the curve; CI: Confidence interval.