Copyright: ©Author(s) 2026.
World J Gastroenterol. Sep 7, 2026; 32(33): 118584
Published online Sep 7, 2026. doi: 10.3748/wjg.118584
Published online Sep 7, 2026. doi: 10.3748/wjg.118584
Table 1 Baseline characteristic of patients, n (%)/median (interquartile range)
| Variable | Non-SNC (n = 756) | SNC (n = 253) | P value |
| T stage | < 0.0011 | ||
| 1 | 89 (12) | 80 (32) | |
| 2 | 667 (88) | 173 (68) | |
| Sex | < 0.0011 | ||
| Female | 303 (40) | 133 (53) | |
| Male | 453 (60) | 120 (47) | |
| Fecal occult blood | 0.241 | ||
| Negative | 173 (23) | 49 (19) | |
| Positive | 583 (77) | 204 (81) | |
| Smoking and alcohol history | 0.131 | ||
| Negative | 585 (77) | 200 (79) | |
| Smoking history | 84 (11) | 35 (14) | |
| Alcohol consumption history | 15 (2.0) | 5 (2.0) | |
| Combined smoking-alcohol history | 72 (9.5) | 13 (5.1) | |
| Surgery history | 0.0561 | ||
| Negative | 82 (11) | 17 (6.7) | |
| Positive | 674 (89) | 236 (93) | |
| Cardiovascular disease | 0.831 | ||
| Negative | 737 (97) | 246 (97) | |
| Positive | 19 (2.5) | 7 (2.8) | |
| Hypertension | 0.881 | ||
| Negative | 267 (35) | 88 (35) | |
| Positive | 489 (65) | 165 (65) | |
| Diabetes | 0.901 | ||
| Negative | 403 (53) | 136 (54) | |
| Positive | 353 (47) | 117 (46) | |
| ABO blood group | 0.471 | ||
| A | 326 (43) | 109 (43) | |
| B | 186 (25) | 55 (22) | |
| AB | 82 (11) | 36 (14) | |
| O | 162 (21) | 53 (21) | |
| RH blood group | 0.992 | ||
| Negative | 5 (1) | 2 (1) | |
| Positive | 751 (99) | 251 (99) | |
| Histological type | < 0.0011 | ||
| Ulcerative | 517 (68) | 133 (53) | |
| Infiltrating | 9 (1.2) | 17 (6.7) | |
| Protruding | 230 (30) | 103 (41) | |
| Differentiation | < 0.0012 | ||
| Poorly differentiated | 114 (15.1) | 15 (6) | |
| Moderately differentiated | 570 (75.4) | 222 (88) | |
| Well differentiated | 72 (9.5) | 15 (6) | |
| Margin | > 0.992 | ||
| Negative | 6 (0.8) | 2 (0.8) | |
| Positive | 750 (99) | 251 (99) | |
| S100 | < 0.0011 | ||
| Negative | 106 (14) | 74 (29) | |
| Positive | 650 (86) | 179 (71) | |
| CD34 | > 0.992 | ||
| Negative | 1 (0.1) | 0 (0) | |
| Positive | 755 (100) | 253 (100) | |
| D2-40 | < 0.0011 | ||
| Negative | 192 (25) | 157 (62) | |
| Positive | 564 (75) | 96 (38) | |
| NRS2002 | < 0.0012 | ||
| 0 | 151 (20) | 61 (24) | |
| 1 | 333 (44) | 95 (38) | |
| 2 | 158 (21) | 59 (23) | |
| 3 | 53 (7.0) | 36 (14) | |
| 4 | 61 (8.1) | 0 (0) | |
| 5 | 0 (0) | 2 (0.8) | |
| Caprini | < 0.0012 | ||
| 0 | 8 (1.1) | 2 (0.8) | |
| 1 | 13 (1.7) | 31 (12) | |
| 2 | 243 (32) | 84 (33) | |
| 3 | 304 (40) | 78 (31) | |
| 4 | 145 (19) | 43 (17) | |
| 5 | 35 (4.6) | 10 (4.0) | |
| 6 | 6 (0.8) | 2 (0.8) | |
| 7 | 2 (0.3) | 3 (1.2) | |
| Eastern Cooperative Oncology Group | < 0.0012 | ||
| 0 | 509 (67) | 225 (89) | |
| 1 | 223 (29) | 26 (10) | |
| 2 | 23 (3.0) | 2 (0.8) | |
| 3 | 1 (0.1) | 0 (0) | |
| Age | 61.000 (53.500-67.500) | 62.000 (57.000-69.000) | 0.0123 |
| Body mass index | 22.676 (20.950-25.000) | 24.030 (23.000-26.600) | < 0.0013 |
| Alfa-fetoprotein | 2.795 (2.235-3.960) | 3.130 (2.530-3.870) | 0.0243 |
| Carcinoembryonic antigen | 2.260 (1.440-3.720) | 2.280 (1.370-3.380) | 0.293 |
| CA19-9 | 10.650 (7.175-15.700) | 11.000 (6.460-15.530) | 0.703 |
| CA724 | 3.210 (1.110-10.070) | 2.510 (0.970-10.070) | 0.0343 |
| CA125 | 10.700 (8.250-14.600) | 11.300 (8.520-15.900) | 0.163 |
| Ki67 | 0.750 (0.600-0.800) | 0.800 (0.600-0.800) | 0.0163 |
- Citation: Kang BY, Bai H, Ni K, Qiao YH, Li YL, Wang YQ, Wang Q, Zhu J, Li JP. Artificial intelligence-integrated multimodal data-assisted magnetic resonance imaging for neoadjuvant chemoradiotherapy decision-making in cT1-2N0 rectal cancer. World J Gastroenterol 2026; 32(33): 118584
- URL: https://www.wjgnet.com/1007-9327/full/v32/i33/118584.htm
- DOI: https://dx.doi.org/10.3748/wjg.118584