Risk of respiratory complications following gastrointestinal endoscopy under monitored anesthesia care: A prospective cohort study

doi:10.3748/wjg.122191

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Aug 14, 2026; 32(30): 122191
Published online Aug 14, 2026. doi: 10.3748/wjg.122191

Table 3 Associations between different sedation levels and respiratory complications during gastrointestinal endoscopy according to a multiple regression model

Item	Respiratory complications, number/total number		OR (95%CI)	P value
Item	MS	DS/GA	OR (95%CI)	P value
Crude model	13/1531	64/5699	1.33 (0.73-2.41)	0.356
Model 1¹	13/1531	64/5699	1.57 (0.84-2.91)	0.155
Model 2²	13/1531	64/5699	2.29 (1.16-4.54)	0.017
Model 3³	13/1531	64/5699	2.75 (1.32-5.71)	0.007

¹Adjusted for American Society of Anesthesiologists classification.

²Additionally, adjusted for heart disease, asthma, hiatus hernia, gastrointestinal ulcer, and gastroesophageal reflux disease.

³Further adjusted for a history of upper gastrointestinal and oral-pharyngeal surgery, as well as regurgitation and aspiration.

OR: Odds ratio; GA: General anesthesia; MS: Moderate sedation; DS: Deep sedation.

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Citation: Ma LX, Zhang LN, Zhu YZ, Wang MH, Du XB, Qi LJ, Sun J, Yi XL, Wang P, Zhou ZG, Ji XY, Zhang L. Risk of respiratory complications following gastrointestinal endoscopy under monitored anesthesia care: A prospective cohort study. World J Gastroenterol 2026; 32(30): 122191
URL: https://www.wjgnet.com/1007-9327/full/v32/i30/122191.htm
DOI: https://dx.doi.org/10.3748/wjg.122191

Ma LX, Zhang LN, Zhu YZ, Wang MH, Du XB, Qi LJ, Sun J, Yi XL, Wang P, Zhou ZG, Ji XY, Zhang L. Risk of respiratory complications following gastrointestinal endoscopy under monitored anesthesia care: A prospective cohort study. World J Gastroenterol 2026; 32(30): 122191 [DOI: 10.3748/wjg.122191]

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