Copyright: ©Author(s) 2026.
World J Gastroenterol. Aug 14, 2026; 32(30): 122191
Published online Aug 14, 2026. doi: 10.3748/wjg.122191
Published online Aug 14, 2026. doi: 10.3748/wjg.122191
Table 1 Baseline characteristics of the study population, mean ± SD/n (%)
| Variables | Total (n = 7230) | MAC | P value | |
| MS (n = 1531) | DS/GA (n = 5699) | |||
| Age (years) | 52.1 ± 12.7 | 53.1 ± 13.1 | 51.9 ± 12.6 | < 0.001 |
| Sex | 0.002 | |||
| Male | 3579 (49.5) | 812 (53.0) | 2767 (48.6) | |
| Female | 3651 (50.5) | 719 (47.0) | 2932 (51.4) | |
| BMI (kg/m2) | 24.7 ± 3.4 | 25.4 ± 4.4 | 24.5 ± 3.1 | < 0.001 |
| ASA classification | < 0.001 | |||
| I | 3012 (41.7) | 452 (29.5) | 2560 (44.9) | |
| II | 3605 (49.9) | 802 (52.4) | 2803 (49.2) | |
| ≥ III | 613 (8.5) | 277 (18.1) | 336 (5.9) | |
| Smoker | 271 (3.7) | 76 (5.0) | 195 (3.4) | 0.005 |
| Alcohol drinker | 311 (4.3) | 70 (4.6) | 241 (4.2) | 0.557 |
| Underlying pulmonary disease | ||||
| Asthma | 82 (1.1) | 43 (2.8) | 39 (0.7) | < 0.001 |
| COPD | 93 (1.3) | 33 (2.2) | 60 (1.1) | < 0.001 |
| Cardiovascular disease | ||||
| Hypertension | 1604 (22.2) | 382 (25.0) | 1222 (21.4) | 0.003 |
| Heart disease | 602 (8.3) | 258 (16.9) | 344 (6.0) | < 0.001 |
| Neurological diseases | ||||
| Cerebrovascular | 104 (1.4) | 60 (3.9) | 44 (0.8) | < 0.001 |
| Depression | 39 (0.5) | 0 (0.0) | 39 (0.7) | 0.001 |
| Diabetes mellitus | 683 (9.4) | 164 (10.7) | 519 (9.1) | 0.057 |
| Gastrointestinal disorders | ||||
| GERD | 541 (7.5) | 355 (23.2) | 186 (3.3) | < 0.001 |
| Hiatus hernia | 84 (1.2) | 46 (3.0) | 38 (0.7) | < 0.001 |
| Gastrointestinal ulcer | 343 (4.7) | 107 (7.0) | 236 (4.1) | < 0.001 |
| Surgical history | ||||
| Upper gastrointestinal surgery | 176 (2.4) | 130 (8.5) | 46 (0.8) | < 0.001 |
| Colorectal surgery | 324 (4.5) | 80 (5.2) | 244 (4.3) | 0.113 |
| Pulmonary surgery | 153 (2.1) | 37 (2.4) | 116 (2.0) | 0.357 |
| Oral-pharyngeal surgery | 40 (0.6) | 32 (2.1) | 8 (0.1) | < 0.001 |
| Intraoperative respiratory adverse events | ||||
| Severe cough | 51 (0.7) | 9 (0.6) | 42 (0.7) | 0.536 |
| Regurgitation and aspiration | 12 (0.2) | 0 (0.0) | 12 (0.2) | 0.083 |
| Hypoxemia | 215 (3.0) | 39 (2.5) | 176 (3.1) | 0.269 |
| Procedure type | 0.063 | |||
| Combined | 5465 (75.6) | 1123 (73.4) | 4342 (76.2) | |
| EGD | 1059 (14.6) | 249 (16.3) | 810 (14.2) | |
| Colonoscopy | 706 (9.8) | 159 (10.4) | 547 (9.6) | |
| Procedure time | 0.102 | |||
| < 10 minutes | 1425 (19.7) | 326 (21.3) | 1099 (19.3) | |
| 10-30 minutes | 5159 (71.4) | 1059 (69.2) | 4100 (71.9) | |
| > 30 minutes | 646 (8.9) | 146 (9.5) | 500 (8.8) | |
| Respiratory complications | 77 (1.1) | 13 (0.8) | 64 (1.1) | 0.354 |
- Citation: Ma LX, Zhang LN, Zhu YZ, Wang MH, Du XB, Qi LJ, Sun J, Yi XL, Wang P, Zhou ZG, Ji XY, Zhang L. Risk of respiratory complications following gastrointestinal endoscopy under monitored anesthesia care: A prospective cohort study. World J Gastroenterol 2026; 32(30): 122191
- URL: https://www.wjgnet.com/1007-9327/full/v32/i30/122191.htm
- DOI: https://dx.doi.org/10.3748/wjg.122191