Five-fraction stereotactic magnetic resonance-guided adaptive radiotherapy targeting the primary tumor in metastatic pancreatic cancer

doi:10.3748/wjg.117832

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Aug 7, 2026; 32(29): 117832
Published online Aug 7, 2026. doi: 10.3748/wjg.117832

Table 1 Patients baseline characteristics, n (%)

Characteristics
Number of patients	24
Sex
Women	11 (46)
Men	13 (54)
Age, median age (range)	65 (49-84)
Age > 75	4 (17)
ECOG score
0	11 (46)
1	11 (46)
2	2 (8)
Location of primary tumor
Head	10 (42)
Body	3 (13)
Tail	2 (8)
Head/body	2 (8)
Body-tail	2 (8)
Local relapse	5 (21)
Onset of metastatic state
Synchronous	13 (54)
Metachronous	11 (46)
Number of metastases
≤ 5 metastases	14 (58)
> 5 metastases	10 (42)
Location of metastases
Liver only	12 (50)
Lung only	4 (17)
Non-regional lymph nodes only	2 (8)
Peritoneal carcinomatosis	4 (17)
Multiple organs	2 (8)
Median CA19.9 at diagnosis of metastatic disease (range)	365 UI/mL (17-2697)
Median CA19.9 before MRgRT (range)	132 UI/mL (10.5-2120)

ECOG: Eastern Cooperative Oncology Group performance status; MRgRT: Magnetic resonance-guided radiotherapy; CA19-9: Carbohydrate antigen 19-9.

Full Size Table

Citation: Schumann MA, Gaasch A, Boyaci S, Fuchs F, Walter F, Marschner SN, Eze C, Westphalen CB, Holch JW, Beyer G, Kunz WG, Mayerle J, Niyazi M, Belka C, Corradini S, Rogowski P. Five-fraction stereotactic magnetic resonance-guided adaptive radiotherapy targeting the primary tumor in metastatic pancreatic cancer. World J Gastroenterol 2026; 32(29): 117832
URL: https://www.wjgnet.com/1007-9327/full/v32/i29/117832.htm
DOI: https://dx.doi.org/10.3748/wjg.117832

Schumann MA, Gaasch A, Boyaci S, Fuchs F, Walter F, Marschner SN, Eze C, Westphalen CB, Holch JW, Beyer G, Kunz WG, Mayerle J, Niyazi M, Belka C, Corradini S, Rogowski P. Five-fraction stereotactic magnetic resonance-guided adaptive radiotherapy targeting the primary tumor in metastatic pancreatic cancer. World J Gastroenterol 2026; 32(29): 117832 [DOI: 10.3748/wjg.117832]

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