Diagnostic efficacy of fecal calprotectin combined with a high-sensitivity quantitative fecal immunochemical test for colorectal tumors

Figure 2 Receiver operating characteristic curves of fecal calprotectin, high-sensitivity quantitative fecal immunochemical test, and their combination. A: Diagnosing adenomas. The area under the receiver operating characteristic curve (AUC) value of fecal calprotectin (FC) for diagnosing adenoma was 0.591 [95% confidence interval (CI): 0.466-0.716], the AUC value of high-sensitivity quantitative fecal immunochemical test (hs-qFIT) for diagnosing adenoma was 0.653 (95%CI: 0.532-0.774), and the AUC value of the combination of the two for diagnosing adenoma was 0.662 (95%CI: 0.543-0.782); B: Diagnosing colorectal cancer (CRC). The AUC value of FC for diagnosing CRC was 0.797 (95%CI: 0.697-0.897), the AUC value of hs-qFIT for diagnosing CRC was 0.872 (95%CI: 0.786-0.958), and the AUC value of the combination of the two for diagnosing CRC was 0.866 (95%CI: 0.784-0.949). FC: Fecal calprotectin; hs-qFIT: High-sensitivity quantitative fecal immunochemical test.