Outpatient visit frequency in patients with overlapping non-erosive reflux disease and epigastric pain syndrome: A multicenter study

doi:10.3748/wjg.119326

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jul 28, 2026; 32(28): 119326
Published online Jul 28, 2026. doi: 10.3748/wjg.119326

Table 4 Interaction effects between significant predictors on outpatient visit frequency

Variables	OR (adjusted)	95%CI	P value
PPIs × age	0.99	0.97-1.01	0.23
PPIs × disease duration of NERD	1.00	0.99-1.00	0.38
PPIs × PHQ-4	1.02	0.92-1.14	0.65
Chinese herbal preparations × PHQ-4	0.95	0.83-1.08	0.39
PPIs × Chinese herbal preparations¹	29.06	8.38-100.72	< 0.001
PPIs × Chinese herbal preparations²	3.03	0.72-12.76	0.13

¹Comparison of outpatient visits (past 3 months) 1-2 times vs 3-4 times.

²Comparison of outpatient visits (past 3 months) 3-4 times vs ≥ 5 times.

OR: Odds ratio; CI: Confidence interval; PPIs: Proton pump inhibitors; NERD: Non-erosive reflux disease; PHQ: Patient Health Questionnaire.

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Citation: Lv M, Liu X, Huang KY, Xu LS, Che H, Yao MX, Wang FY. Outpatient visit frequency in patients with overlapping non-erosive reflux disease and epigastric pain syndrome: A multicenter study. World J Gastroenterol 2026; 32(28): 119326
URL: https://www.wjgnet.com/1007-9327/full/v32/i28/119326.htm
DOI: https://dx.doi.org/10.3748/wjg.119326

Lv M, Liu X, Huang KY, Xu LS, Che H, Yao MX, Wang FY. Outpatient visit frequency in patients with overlapping non-erosive reflux disease and epigastric pain syndrome: A multicenter study. World J Gastroenterol 2026; 32(28): 119326 [DOI: 10.3748/wjg.119326]

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