Early postoperative negative conversion of Helicobacter pylori stool antigen after distal gastrectomy and potential host-related factors

doi:10.3748/wjg.118887

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jul 28, 2026; 32(28): 118887
Published online Jul 28, 2026. doi: 10.3748/wjg.118887

Table 3 Primary multivariable logistic regression for early negative conversion (maximum likelihood estimation vs Firth)

Variable	MLE OR (95%CI)	MLE P value	Firth OR (95%CI)	Firth P value
American Society of Anesthesiologists score (per 1-point increase)	3.02 (0.91-10.01)	0.071	2.55 (0.83-7.85)	0.104
Age (per 1-year increase)	1.02 (0.96-1.07)	0.592	1.01 (0.96-1.07)	0.629
Body mass index (per 1 kg/m² increase)	1.09 (0.87-1.36)	0.46	1.07 (0.87-1.33)	0.507
Sex (female vs male)	0.48 (0.11-2.03)	0.319	0.51 (0.13-2.07)	0.346
Postoperative antibiotics use (yes vs no)	1.85 (0.19-18.07)	0.596	1.46 (0.19-11.01)	0.716

Firth: Firth penalized logistic regression (sensitivity analysis to reduce small-sample bias); MLE: Maximum likelihood estimation; OR: Odds ratio.

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Citation: Khenmedekh GO, Kim DH, Ryu DH, Yoo KC. Early postoperative negative conversion of Helicobacter pylori stool antigen after distal gastrectomy and potential host-related factors. World J Gastroenterol 2026; 32(28): 118887
URL: https://www.wjgnet.com/1007-9327/full/v32/i28/118887.htm
DOI: https://dx.doi.org/10.3748/wjg.118887

Khenmedekh GO, Kim DH, Ryu DH, Yoo KC. Early postoperative negative conversion of Helicobacter pylori stool antigen after distal gastrectomy and potential host-related factors. World J Gastroenterol 2026; 32(28): 118887 [DOI: 10.3748/wjg.118887]

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