Hua-Zhuo-Jie-Du formula alleviates colitis-associated colorectal cancer via regulating phosphatidylinositol 3-kinase/protein kinase B signaling pathway

Table 2 Fifty-two core targets of Hua-Zhuo-Jie-Du formula for colitis-associated colorectal cancer

No.	Target	Degree	No.	Target	Degree	No.	Target	Degree
1	SRC	68	19	HSP90AA1	36	37	TNF	26
2	AKT1	64	20	ERBB2	36	38	MAPK14	26
3	TP53	64	21	MAPK8	34	39	CCND1	26
4	ESR1	60	22	EP300	34	40	MAPK12	26
5	STAT3	54	23	HIF1A	34	41	PRKCD	26
6	JUN	48	24	CREBBP	32	42	AR	24
7	EGFR	46	25	FOS	32	43	FYN	24
8	MAPK1	46	26	IGF1R	30	44	IKBKB	24
9	PIK3CA	44	27	GRB2	30	45	PLCG1	24
10	MAPK3	42	28	PTK2	30	46	PTPN6	22
11	PIK3R1	42	29	CDC42	30	47	CHUK	22
12	CTNNB1	40	30	STAT1	30	48	VAV1	22
13	AKT2	38	31	BCL2	28	49	MAP3K7	20
14	RELA	38	32	MAPK9	28	50	IL6	20
15	PTPN11	36	33	MDM2	28	51	IKBKG	20
16	NFKB1	36	34	HSP90AB1	28	52	CASP3	20
17	PIK3CD	36	35	RAF1	28
18	PIK3CB	36	36	HDAC1	26