Clinical assessment of malnutrition among patients with alcoholic liver cirrhosis: A single-center study in Southern China

doi:10.3748/wjg.v32.i26.118957

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jul 14, 2026; 32(26): 118957
Published online Jul 14, 2026. doi: 10.3748/wjg.v32.i26.118957

Table 2 Nutritional status analysis with hepatitis B virus-related cirrhosis, and alcoholic liver cirrhosis and healthy controls, n (%)/median (interquartile range)

Variables	HCs (n = 83)	HBV-C (n = 103)	ALC (n = 249)	P value
Anthropometric
WC (cm)	76.50 (74.00-86.00)	80.50 (76.00-86.00)	85.00 (80.00-89.00)^a^,^b	0.002
HC (cm)	88.00 (80.00-91.00)	82.00 (80.00-87.00)	90.00 (84.00-93.00)^b	< 0.001
WHR	0.92 (0.89-0.97)	0.97 (0.95-1.01)^a	0.95 (0.92-1.01)^a^,^b	0.002
AC (cm)	26.00 (24.00-28.00)	24.00 (22.00-25.00)^a	25.00 (23.00-28.00)^b	< 0.001
AMC (cm)	21.00 (19.20-22.30)	20.20 (18.20-21.50)	21.90 (20.10-24.50)^b	< 0.001
TSF (mm)	12.00 (10.00-18.00)	10.00 (8.00-12.00)	10.00 (8.00-13.00)	0.142
AFT (mm)	18.00 (12.00-28.00)	10.00 (10.00-16.00)^a	18.50 (10.25-30.00)^b	< 0.001
Serum trace elements
Fe (μmol/L)	14.50 (10.12-20.35)	9.70 (5.60-17.70)^a	8.75 (4.00-16.33)^a	0.002
Zn (μmol/L)	10.20 (7.65-11.70)	8.60 (7.00-10.30)	9.80 (7.97-11.27)	0.096
Mg (mmol/L)	0.88 (0.84-0.93)	0.84 (0.79-0.89)^a	0.79 (0.72-0.86)^a^,^b	< 0.001
Cu (μmol/L)	15.50 (12.80-18.75)	13.10 (11.50-18.20)	14.90 (13.05-18.00)	0.343
AdCa (mmol/L)	2.29 (2.23-2.36)	2.29 (2.23-2.36)	2.35 (2.27-2.44)^a^,^b	< 0.001
Serum vitamins
VA (μmol/L)	1.36 (1.26-1.49)	1.32 (1.21-1.43)	1.39 (1.22-1.58)	0.185
VB1 (nmol/L)	78.54 (55.85-93.38)	88.42 (70.96-98.37)	72.98 (60.79-87.23)^a^,^b	0.017
VB2 (μg/L)	326.70 (294.21-358.53)	322.07 (297.53-359.03)	291.85 (270.09-352.24)^a^,^b	0.008
VB6 (μmol/L)	19.09 (13.68-25.98)	20.70 (13.95-26.19)	20.60 (15.37-25.37)	0.565
VB9 (nmol/L)	20.55 (17.57-22.43)	18.56 (16.56-21.79)	19.45 (17.47-22.19)	0.238
VC (μmol/L)	37.61 (32.64-42.04)	42.90 (36.32-51.75)^a	46.29 (43.16-49.36)^a	< 0.001
VE (μg/mL)	12.79 (11.73-14.07)	15.06 (13.60-16.86)^a	15.20 (13.51-16.44)^a	< 0.001
VB12 (pg/mL)	279.94 (215.12-319.18)	281.12 (211.05-356.19)	279.21 (201.41-349.65)	0.713
VD (nmol/L)	57.65 (44.53-68.67)	57.85 (48.75-67.03)	46.20 (37.66-57.25)^a^,^b	< 0.001
Nutritional assessment tools
SGA				0.153
1 (well-nourished)	74 (89.16)	89 (86.41)	195 (80.91)
2 (malnourished)	9 (10.84)	14 (13.59)	46 (19.09)
NRS-2002				0.243
1 (no nutritional risk)	73 (87.95)	86 (83.50)	183 (79.91)
2 (at nutritional risk)	10 (12.05)	17 (16.50)	46 (20.09)

^aP < 0.05 for alcoholic liver cirrhosis or hepatitis B virus-related cirrhosis vs healthy controls.

^bP < 0.05 for alcoholic liver cirrhosis vs hepatitis B virus-related cirrhosis.

ALC: Alcoholic liver cirrhosis; HBV-C: Hepatitis B virus-related cirrhosis; HCs: Healthy controls; WC: Waist circumference; HC: Hip circumference; WHR: Waist-to-hip ratio; AC: Mid-arm circumference; AMC: Mid-arm muscular circumference; TSF: Triceps skinfold; AFT: Abdominal fat thickness; Fe: Iron; Zn: Zinc; Mg: Magnesium; Cu: Copper; AdCa: Adjusted calcium; VB: Vitamin B; VA: Vitamin A; VC: Vitamin C; VD: Vitamin D; VE: Vitamin E; SGA: Subjective global assessment; NRS-2002: Nutritional risk screening 2002.

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Citation: Wu XQ, Liu YY, Yu HS, Abassa KK, Pan LL, Ke BL, Guo YW. Clinical assessment of malnutrition among patients with alcoholic liver cirrhosis: A single-center study in Southern China. World J Gastroenterol 2026; 32(26): 118957
URL: https://www.wjgnet.com/1007-9327/full/v32/i26/118957.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i26.118957

Wu XQ, Liu YY, Yu HS, Abassa KK, Pan LL, Ke BL, Guo YW. Clinical assessment of malnutrition among patients with alcoholic liver cirrhosis: A single-center study in Southern China. World J Gastroenterol 2026; 32(26): 118957 [DOI: 10.3748/wjg.v32.i26.118957]

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