Risk factors and fatigue in difficult-to-treat Crohn’s disease: A cross-sectional study of a Chinese cohort

Table 4 Multiplevariable linear regression analysis of factors associated with fatigue in difficult-to-treat Crohn’s disease patients

Characteristics	Total scores		General fatigue		Physical fatigue		Mental fatigue		Reduced activity		Reduced motivation
	Coefficient (95%CI)	P value	Coefficient (95%CI)	P value	Coefficient (95%CI)	P value	Coefficient (95%CI)	P value	Coefficient (95%CI)	P value	Coefficient (95%CI)	P value
Partial enteral nutrition	7.023 (0.240-13.806)	0.043	2.286 (0.534-4.038)	0.011	2.087 (0.296-3.877)	0.033	-	-	-	-	1.955 (0.358-3.552)	0.017
A3	14.328 (1.552-27.103)	0.029	-	-	3.806 (0.407-7.206)	0.029	-	-	-	-	3.385 (0.451-6.320)	0.024
B2	-	-	-	-	-	-	-	-	-	-	-1.816 (-3.342 to -0.289)	0.02
B3	-	-	-	-	-	-	-	-	-	-	-2.810 (-5.099 to -0.520)	0.017
Surgical history	-	-	-	-	-	-	-	-	1.621 (0.210-3.033)	0.025	-	-
Disease activity	-	-	-	-	2.540 (0.531-4.549)	0.014	-	-	-	-	-	-
	n = 88		n = 90		n = 88		n = 88		n = 88		n = 88

Variable in the model: (1) C-reactive protein; (2) Vitamin B12; (3) Hemoglobin; (4) Ca; (5) Fe; (6) Partial enteral nutrition; (7) Total enteral nutrition; (8) B2; (9) B3; (10) B2 + B3; (11) A2; (12) A3; (13) L2; (14) L3; (15) L1 + L4; (16) L2 + L4; (17) L3 + L4; and (18) Disease activity. Only statistically significant associations (P < 0.05) are shown in detail.