Radiotherapy-free neoadjuvant strategy using sintilimab plus XELOX in locally advanced rectal cancer: A single-arm phase II trial

doi:10.3748/wjg.117924

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jul 14, 2026; 32(26): 117924
Published online Jul 14, 2026. doi: 10.3748/wjg.117924

Table 4 Multivariable logistic regression analysis of clinical risk assessment factors

Characteristic	P value	OR	95%CI
BMI before treatment (> 24 kg/m²)	0.06	6.72	1.04-66.3
CRM (threatened)	0.11	5.97	0.732-68.1
Tumor size (> 4 cm)	0.036	6.51	1.23-45.2
Before treatment CEA (> 5 ng/mL)	0.035	0.12	0.01-0.73

BMI: Body mass index; CRM: Circumferential resection margin; CEA: Carcinoembryonic antigen; OR: Odds ratio; CI: Confidence interval.

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Citation: Qiang WD, Wei Q, Yang B, Chen WJ, Lin CQ, Li YX. Radiotherapy-free neoadjuvant strategy using sintilimab plus XELOX in locally advanced rectal cancer: A single-arm phase II trial. World J Gastroenterol 2026; 32(26): 117924
URL: https://www.wjgnet.com/1007-9327/full/v32/i26/117924.htm
DOI: https://dx.doi.org/10.3748/wjg.117924

Qiang WD, Wei Q, Yang B, Chen WJ, Lin CQ, Li YX. Radiotherapy-free neoadjuvant strategy using sintilimab plus XELOX in locally advanced rectal cancer: A single-arm phase II trial. World J Gastroenterol 2026; 32(26): 117924 [DOI: 10.3748/wjg.117924]

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