CRAPT-M: An effective prognostic predictor for hepatocellular carcinoma patients treated with locoregional-bevacizumab-immunotherapy

doi:10.3748/wjg.119588

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World Journal of Gastroenterology

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1007-9327

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jul 7, 2026; 32(25): 119588
Published online Jul 7, 2026. doi: 10.3748/wjg.119588

Table 4 Treatments efficacy, n (%)

Variables	Overall (n = 443)	CRAPT-M-low-/intermediate-risk (n = 220)	CRAPT-M-high-risk (n = 223)	P value
RECIST				0.059
CR	2 (0.5)	0 (0.0)	2 (0.9)
PR	155 (35.0)	83 (37.7)	72 (32.3)
SD	223 (50.3)	114 (51.8)	109 (48.9)
PD	63 (14.2)	23 (10.5)	40 (17.9)
mRECIST				0.08
CR	21 (4.7)	12 (5.5)	9 (4.0)
PR	236 (53.3)	127 (57.7)	109 (48.9)
SD	123 (27.8)	58 (26.4)	65 (29.1)
PD	63 (14.2)	23 (10.5)	40 (17.9)
ORR	157 (35.4)	83 (37.7)	74 (33.2)	0.368
mORR	257 (58.0)	139 (63.2)	118 (52.9)	0.036
DCR	380 (85.8)	197 (89.5)	183 (82.1)	0.034

RECIST: Response Evaluation Criteria in Solid Tumors; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease; mRECIST: Modified Response Evaluation Criteria in Solid Tumors; ORR: Objective response rate; mORR: Modified objective response rate; DCR: Disease control rate.

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Citation: Zheng ZH, Xiao R, Liu N, He BY, Yu W, Wu ZS, Chen MS, Mei J, Hu DD, Guo RP. CRAPT-M: An effective prognostic predictor for hepatocellular carcinoma patients treated with locoregional-bevacizumab-immunotherapy. World J Gastroenterol 2026; 32(25): 119588
URL: https://www.wjgnet.com/1007-9327/full/v32/i25/119588.htm
DOI: https://dx.doi.org/10.3748/wjg.119588

Zheng ZH, Xiao R, Liu N, He BY, Yu W, Wu ZS, Chen MS, Mei J, Hu DD, Guo RP. CRAPT-M: An effective prognostic predictor for hepatocellular carcinoma patients treated with locoregional-bevacizumab-immunotherapy. World J Gastroenterol 2026; 32(25): 119588 [DOI: 10.3748/wjg.119588]

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