Novel inflammation-based model for postoperative early recurrence prediction of hepatitis B virus-related hepatocellular carcinoma ≤ 5 cm

doi:10.3748/wjg.119364

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jul 7, 2026; 32(25): 119364
Published online Jul 7, 2026. doi: 10.3748/wjg.119364

Table 1 Baseline characteristic of all patients with hepatitis B virus-related hepatocellular carcinoma ≤ 5 cm

Parameter	n = 650
Age (year)	52 (44-60)
≤ 60/> 60	495 (76.2)/155 (23.8)
Sex (female/male)	81 (12.5)/569 (87.5)
Smoking (no/yes)	421 (64.8)/229 (35.2)
Drinking (no/yes)	506 (77.8)/144 (22.2)
Diabetes (no/yes)	593 (91.2)/57 (8.8)
Hypertension (no/yes)	572 (88.0)/78 (12.0)
Cirrhosis (no/yes)	215 (33.1)/435 (66.9)
Anti-HCV (negative/positive)	645 (99.2)/5 (0.8)
HBV-DNA (copy/mL; ≤ 1000/> 1000)	350 (53.8)/300 (46.2)
HBeAg (negative/positive)	564 (86.8)/86 (13.2)
AFP (ng/mL; ≤ 400/> 400)	480 (73.8)/170 (26.2)
Diameter (cm)	3.0 (2.3-3.8)
≤ 3/> 3	335 (51.5)/315 (48.5)
Number (1/2/≥ 3)	516 (79.4)/89 (13.7)/45 (6.9)
Differentiation (well/medium-poor)	123 (18.9)/527 (81.1)
Vascular invasion (no/yes)	582 (89.5)/68 (10.5)
MVI (no/yes)	477 (73.4)/173 (26.6)
Child-Pugh grade (A/B)	629 (96.8)/21 (3.2)
BCLC stage (0/A/B/C)	89 (13.7)/433 (66.6)/59 (9.1)/69 (10.6)
AJCC-TNM, 8^th (I/II/III)	467 (71.8)/169 (26.0)/14 (2.2)
CNLC (I/II/III)	535 (82.3)/47 (7.2)/68 (10.5)
Recurrence (no/early/Late)	353 (54.3)/222 (34.2)/75 (11.5)

The data were showed as n (%) or median (interquartile ranges). HCV: Hepatitis C virus; HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen; AFP: Alpha-fetoprotein; MVI: Microvascular invasion; BCLC: Barcelona Clinic Liver Cancer; AJCC-TNM: American Joint Committee on Cancer Tumor-Node-Metastasis; CNLC: China Liver Cancer.

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Citation: Dai TX, Li J, Li H, Wang GY. Novel inflammation-based model for postoperative early recurrence prediction of hepatitis B virus-related hepatocellular carcinoma ≤ 5 cm. World J Gastroenterol 2026; 32(25): 119364
URL: https://www.wjgnet.com/1007-9327/full/v32/i25/119364.htm
DOI: https://dx.doi.org/10.3748/wjg.119364

Dai TX, Li J, Li H, Wang GY. Novel inflammation-based model for postoperative early recurrence prediction of hepatitis B virus-related hepatocellular carcinoma ≤ 5 cm. World J Gastroenterol 2026; 32(25): 119364 [DOI: 10.3748/wjg.119364]

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