Baseline multimodal clinical-radiomics-pathomics model predicts mucosal healing in Crohn’s disease after infliximab therapy

Figure 2 Feature selection and performance evaluation of the radiomics score (rad score) and pathomics score (pat score) in ileal Crohn’s disease via least absolute shrinkage and selection operator logistic regression. A: Selection of the tuning parameter (λ) in the least absolute shrinkage and selection operator model through 10-fold cross validation based on the minimum criterion. The binomial deviance from cross validation is plotted against the log transformed λ [ln(λ)]; B: Coefficient profiles of all features in relation to ln(λ). Features with non-zero coefficients subsequent to regularization are presented; C: The 20 features with non-zero coefficients and their respective contributions to the rad score and pat score; D: The verified sets of the rad score and pat score. LASSO: Least absolute shrinkage and selection operator.