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Retrospective Study
Copyright: ©Author(s) 2026.
World J Gastroenterol. Jul 7, 2026; 32(25): 118842
Published online Jul 7, 2026. doi: 10.3748/wjg.118842
Figure 2
Figure 2 Digital spatial profiling of formalin-fixed, paraffin-embedded samples from gastric intestinal metaplasia patients. A: Representative hematoxylin-eosin and immunofluorescence staining of regions of interest (ROIs); B: Principal component analysis for dimensionality reduction, visualizing all ROIs based on overall gene expression profiles, including the start of observation was defined as the time of the first gastroscopic biopsy [non-progression group (N)] N1-intestinal metaplasia (IM) (red color), progression group (P group) P1-IM (purple color), P2-IM (pink color), and P2-cancerous lesions (blue color). N group: Non-progression group; P group: Progression group; IF: Immunofluorescence; HE: Hematoxylin-eosin; PanCK: Pan-cytokeratin; CD: Cluster of differentiation; CTR: Containing normal tissue; IM: Intestinal metaplasia.


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