Calcium-dependent signaling protein family member S100A11 promotes liver and adipose lipid accumulation through fibroblast growth factor 21

Figure 5 Fibroblast growth factor 21 may play a crucial role in promoting S100A11-mediated lipogenesis. Proteomic analysis of liver tissues from high-fat diet-fed male mice. A: Heatmap of differentially expressed genes according to the threshold of |fold change| ≥ 1.5 with a false discovery rate-adjusted P < 0.05 (Benjamini-Hochberg method); B: Distribution of enriched Kyoto Encyclopedia of Genes And Genomes pathway; C: Class of enriched Kyoto Encyclopedia of Genes And Genomes pathway; D: Gene heatmap enriched in the peroxisome proliferator-activated receptor signaling pathway. n = 4 mice/group. WT: Wild type.