Curcumin nanoparticles mitigate early inflammation in severe acute pancreatitis by modulating peritoneal macrophage polarization via Nrf2/HO-1 pathway activation

doi:10.3748/wjg.118140

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jul 7, 2026; 32(25): 118140
Published online Jul 7, 2026. doi: 10.3748/wjg.118140

Table 2 Primer sequences for reverse transcription quantitative polymerase chain reaction analysis

Primer name	Positive sequence (5′→3′)	Reverse sequence (5′→3′)
iNOS	CTTGGAGCGAGTTGTGGATTG	CCTCTTGTCTTTGACCCAGTAGC
CD163	ATGGCACAGGTCATTCAACCC	TCTGTCGTCGCTTCAGAGTCC
Nrf2	TTAAGCAGCATACAGCAGGACAT	GGACAGTGGTAGTCTCAGCCT
HO-1	GTGACAGAAGAGGCTAAGAC	GTAGTATCTTGAACCAGGCTAG
GAPDH	GGCACAGTCAAGGCTGAGAATG	ATGGTGGTGAAGACGCCAGTA

CD163: Cluster of differentiation 163; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; iNOS: Inducible nitric oxide synthase; HO-1: Heme oxygenase-1; Nrf2: Nuclear factor erythroid 2-related factor 2.

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Citation: Yang L, Liao DX, Wang XY, Fan YH, Luo ZL, Wen Y. Curcumin nanoparticles mitigate early inflammation in severe acute pancreatitis by modulating peritoneal macrophage polarization via Nrf2/HO-1 pathway activation. World J Gastroenterol 2026; 32(25): 118140
URL: https://www.wjgnet.com/1007-9327/full/v32/i25/118140.htm
DOI: https://dx.doi.org/10.3748/wjg.118140

Yang L, Liao DX, Wang XY, Fan YH, Luo ZL, Wen Y. Curcumin nanoparticles mitigate early inflammation in severe acute pancreatitis by modulating peritoneal macrophage polarization via Nrf2/HO-1 pathway activation. World J Gastroenterol 2026; 32(25): 118140 [DOI: 10.3748/wjg.118140]

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