Abdominal nodular histiocytic/mesothelial hyperplasia - intraoperative pitfalls, differential diagnosis, literature review: A case report

doi:10.3748/wjg.116783

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jul 7, 2026; 32(25): 116783
Published online Jul 7, 2026. doi: 10.3748/wjg.116783

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Figure 3 Immunohistochemical findings. A: Immunohistochemical analyses showing cytokeratin AE1/AE3 positivity in both epithelial and mesothelial cell components [immunohistochemistry (IHC); original magnification 200 ×]; B: Intestinal differentiation marker CDX2 mildly expressed in sparse nuclei of neoplastic cells, indicating a gastric origin (IHC; original magnification 200 ×); C: Immunoexpression of calretinin in mesothelial cells (IHC; original magnification 200 ×); D: Note CD68 immunopositivity highlighting the histiocytic component of nodular histiocytic/mesothelial hyperplasia, while mesothelial cells are negative (IHC; original magnification 200 ×).

Citation: Colombo P, Dani G, Saracini B, Castoro C, Spaggiari P. Abdominal nodular histiocytic/mesothelial hyperplasia - intraoperative pitfalls, differential diagnosis, literature review: A case report. World J Gastroenterol 2026; 32(25): 116783
URL: https://www.wjgnet.com/1007-9327/full/v32/i25/116783.htm
DOI: https://dx.doi.org/10.3748/wjg.116783

Colombo P, Dani G, Saracini B, Castoro C, Spaggiari P. Abdominal nodular histiocytic/mesothelial hyperplasia - intraoperative pitfalls, differential diagnosis, literature review: A case report. World J Gastroenterol 2026; 32(25): 116783 [DOI: 10.3748/wjg.116783]

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