Immediate post-polypectomy bleeding is associated with an increased risk of delayed post-polypectomy bleeding: A large retrospective cohort study

Table 2 Risk factors for delayed post-polypectomy bleeding among immediate post-polypectomy bleeding patients

Variable	Univariate OR (95%CI)	P value	Multivariable1 OR (95%CI)	P value
Patient-related factor
Age (per year)	1.007 (0.977-1.039)	0.6355
Male sex	0.787 (0.391-1.584)	0.5018
BMI	0.847 (0.758-0.947)	0.0037	0.901 (0.797-1.018)	0.0930
Hypertension	1.109 (0.525-2.344)	0.7859
Diabetes mellitus	1.299 (0.598-2.818)	0.5084
Chronic kidney disease	1.754 (0.806-3.820)	0.1570	1.699 (0.707-4.082)	0.2362
Polyp-related factors
Polyp number	1.105 (1.027-1.187)	0.0071	1.041 (0.939-1.156)	0.4437
Polyp size (per mm)	1.105 (1.059-1.152)	< 0.0001	1.056 (0.989-1.129)	0.1050
Polyp size ≥ 10 mm	3.461 (1.700-7.048)	0.0006	Excluded2
Non-adenomatous polyp	0.318 (0.095-1.068)	0.0639	0.364 (0.106-1.243)	0.1067
Procedure-related factors
Procedure time (per minute)	1.013 (1.000-1.025)	0.0470	0.997 (0.978-1.017)	0.7651
Withdrawal time (minute)	1.016 (1.003-1.029)	0.0157	Excluded2
Trainee endoscopist	2.224 (0.913-5.417)	0.0784	3.091 (1.037-9.219)	0.0429

¹Multivariable model included variables with P < 0.2 in univariate analysis.

²Excluded from multivariable model: Polyp size ≥ 10 mm due to collinearity with continuous polyp size; Withdrawal time due to collinearity with total procedure time.

Bold P value indicates P < 0.2 in univariate analysis or P < 0.05 in multivariable analysis. OR: Odds ratio; CI: Confidence interval; BMI: Body mass index.