Comparative evaluation of multimodal large language models for Mayo Endoscopic Subscore grading in ulcerative colitis

doi:10.3748/wjg.118690

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 28, 2026; 32(24): 118690
Published online Jun 28, 2026. doi: 10.3748/wjg.118690

Table 5 Diagnostic accuracy by Mayo Endoscopic Subscore grade among physicians and multimodal large language models

MES grade	0	1	2	3
Expert 1	100	53.4	81.8	82.9
Expert 2	98.2	67.1	66.7	62.9
GPT-5	86.5	56.3	62.4	87.1
GPT-4o	85.3	45.2	53.8	52.2
Gemini-2.5-Pro	93.1	38.9	45.4	60.0
Grok-4	88.9	30.1	35.1	40.3
Qwen-VL-Max	76.7	26.3	33.3	38.5

MES: Mayo Endoscopic Subscore.

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Citation: Zhao XY, Shen Y, He JJ, Zhou QY, Jiang LS, Zhou ZR, An FM, Zhan Q, Sun J, Feng W. Comparative evaluation of multimodal large language models for Mayo Endoscopic Subscore grading in ulcerative colitis. World J Gastroenterol 2026; 32(24): 118690
URL: https://www.wjgnet.com/1007-9327/full/v32/i24/118690.htm
DOI: https://dx.doi.org/10.3748/wjg.118690

Zhao XY, Shen Y, He JJ, Zhou QY, Jiang LS, Zhou ZR, An FM, Zhan Q, Sun J, Feng W. Comparative evaluation of multimodal large language models for Mayo Endoscopic Subscore grading in ulcerative colitis. World J Gastroenterol 2026; 32(24): 118690 [DOI: 10.3748/wjg.118690]

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