Early recurrence risk stratification of hepatocellular carcinoma receiving preoperative radiotherapy: Incorporating clinical and imaging features across treatment phases

doi:10.3748/wjg.v32.i23.118308

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 21, 2026; 32(23): 118308
Published online Jun 21, 2026. doi: 10.3748/wjg.v32.i23.118308

Table 4 C-index of the prognostic models and major staging systems

Models	C-index	Bootstrap C-index	P value	P value
Baseline model	0.707 (0.627-0.787)	0.686 (0.600-0.770)	0.010	0.011
Baseline-preoperative model	0.779 (0.714-0.844)	0.751 (0.675-0.824)	Reference	0.704
Preoperative model	0.634 (0.563-0.705)	0.631 (0.552-0.696)	< 0.001	< 0.001
Pre-postoperative model	0.673 (0.593-0.753)	0.660 (0.627-0.784)	0.018	0.007
Postoperative combined model	0.786 (0.717-0.855)	0.758 (0.678-0.834)	0.704	Reference
BCLC stage	0.508 (0.430-0.585)	0.530 (0.497-0.607)	< 0.001	< 0.001
TNM stage	0.526 (0.450-0.602)	0.512 (0.428-0.540)	< 0.001	< 0.001
CNLN stage	0.548 (0.462-0.634)	0.516 (0.476-0.554)	< 0.001	< 0.001

BCLC: Barcelona Clinic Liver Cancer; TNM: Tumor-node-metastasis; CNLC: China liver cancer.

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Citation: Cong R, Chen B, Cheng SN, Zhai YR, Wu F, Feng B, Wang LY, Chen ZW, Zhu YJ, Ma XH, Zhao XM. Early recurrence risk stratification of hepatocellular carcinoma receiving preoperative radiotherapy: Incorporating clinical and imaging features across treatment phases. World J Gastroenterol 2026; 32(23): 118308
URL: https://www.wjgnet.com/1007-9327/full/v32/i23/118308.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i23.118308

Cong R, Chen B, Cheng SN, Zhai YR, Wu F, Feng B, Wang LY, Chen ZW, Zhu YJ, Ma XH, Zhao XM. Early recurrence risk stratification of hepatocellular carcinoma receiving preoperative radiotherapy: Incorporating clinical and imaging features across treatment phases. World J Gastroenterol 2026; 32(23): 118308 [DOI: 10.3748/wjg.v32.i23.118308]

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