Mediating roles of insulin resistance and inflammatory markers between healthy sleep scores and metabolic dysfunction-associated steatotic liver disease

Table 2 Association between the individual components and total score of healthy sleep score with metabolic dysfunction-associated steatotic liver disease

	n (%)	Model 11		Model 22		Model 33
		OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Sleep patterns	7871 (100)
Sleep 7-8 hours/day	4766 (60.55)	0.94 (0.84-1.05)	0.291	0.95 (0.85-1.07)	0.394	0.91 (0.80-1.04)	0.156
Early chronotype	5508 (69.98)	0.73 (0.65-0.83)	< 0.001	0.73 (0.64-0.83)	< 0.001	0.72 (0.62-0.83)	< 0.001
Never/rarely insomnia	5981 (75.99)	0.98 (0.86-1.11)	0.755	0.98 (0.86-1.11)	0.754	0.84 (0.72-0.97)	0.017
No apnea symptoms	7695 (97.76)	0.57 (0.41-0.78)	< 0.001	0.57 (0.42-0.79)	< 0.001	0.68 (0.47-0.98)	0.040
No excessive daytime sleepiness	2549 (32.38)	0.89 (0.79-1.00)	0.050	0.89 (0.79-1.00)	0.050	0.83 (0.72-0.95)	0.005
Healthy sleep score	7871 (100)	0.90 (0.85-0.95)	0.001	0.90 (0.85-0.95)	< 0.001	0.85 (0.80-0.91)	< 0.001
0-2	1625 (20.65)	Reference		Reference		Reference
3	2512 (31.91)	0.94 (0.81-1.01)	0.444	0.95 (0.81-1.10)	0.466	0.88 (0.74-1.05)	0.145
4	2631 (33.43)	0.78 (0.67-0.91)	0.001	0.78 (0.67-0.91)	0.002	0.70 (0.59-0.84)	< 0.001
5	1103 (14.01)	0.76 (0.62-0.91)	0.004	0.76 (0.63-0.92)	0.005	0.65 (0.52-0.80)	< 0.001
P for trend			0.001		0.001		< 0.001

¹Model 1: Adjusted for age and gender.

²Model 2: Adjusted for age, gender, physical exercise, smoking, education.

³Model 3: Adjusted for age, gender, physical exercise, smoking, education, body mass index, hypertension and diabetes.

Data are presented as the logistic regression index (95%CI).