Effects of Lactiplantibacillus plantarum 299v and Lactiplantibacillus plantarum GOS42 on gastrointestinal symptoms in healthy adults with occasional constipation

doi:10.3748/wjg.v32.i21.117959

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 7, 2026; 32(21): 117959
Published online Jun 7, 2026. doi: 10.3748/wjg.v32.i21.117959

Table 1 Summary of subject data at baseline, mean ± SD or n (%)

	ITT L. plantarum (n = 50)	ITT placebo (n = 50)	PP L. plantarum (n = 49)	PP placebo (n = 48)
Women	38 (76)	40 (80)	37 (76)	38 (79)
Age (year)	44.3 ± 13.3	43.8 ± 11.9	44.0 ± 13.3	43.9 ± 12.1
BMI (kg/m²)	28.4 ± 7.9	27.8 ± 6.1	28.5 ± 7.9	28.0 ± 6.1
Fiber intake (g/day)	16.4 ± 8.2	14.4 ± 6.2	16.4 ± 8.2	14.2 ± 6.2
Exercise regularly	31 (62)	31 (62)	30 (61)	29 (60)

No significant differences at baseline between intervention groups. ITT: Intention-to-treat; PP: Per-protocol; L. plantarum: Lactiplantibacillus plantarum; BMI: Body mass index.

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Citation: Önning G, Vegge CS, Montelius C, Lewis ED, Al-Wahsh H, Moulin M, Crowley DC, Guthrie N. Effects of Lactiplantibacillus plantarum 299v and Lactiplantibacillus plantarum GOS42 on gastrointestinal symptoms in healthy adults with occasional constipation. World J Gastroenterol 2026; 32(21): 117959
URL: https://www.wjgnet.com/1007-9327/full/v32/i21/117959.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i21.117959

Önning G, Vegge CS, Montelius C, Lewis ED, Al-Wahsh H, Moulin M, Crowley DC, Guthrie N. Effects of Lactiplantibacillus plantarum 299v and Lactiplantibacillus plantarum GOS42 on gastrointestinal symptoms in healthy adults with occasional constipation. World J Gastroenterol 2026; 32(21): 117959 [DOI: 10.3748/wjg.v32.i21.117959]

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