Yin Yang 1-associated protein 1: Clinical significance and underlying functional mechanisms in gastric cancer

doi:10.3748/wjg.v32.i21.116527

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 7, 2026; 32(21): 116527
Published online Jun 7, 2026. doi: 10.3748/wjg.v32.i21.116527

Table 1 Correlations between Yin Yang 1-associated protein 1 expression with patients’ features

Clinicopathologic features	Cases (n = 118)	YY1AP1 level		P value
Clinicopathologic features	Cases (n = 118)	Low (n = 56)	High (n = 62)	P value
Age				0.670
≤ 55 years	44	22	22
> 55 years	74	34	40
Gender				0.443
Female	36	19	17
Male	82	37	45
Localization				0.643
Upper	16	6	10
Middle	55	26	29
Lower	47	24	23
Tumor size				0.017
≤ 5.0 cm	58	34	24
> 5.0 cm	60	22	38
T stage				0.012
T1-T2	49	30	19
T3-T4	69	26	43
Differentiation				0.982
Well	12	6	6
Moderate	57	27	30
Poor	49	23	26
TNM stage				0.018
I-II	56	33	23
III-IV	62	23	39

TNM: Tumor-node-metastasis; YY1AP1: Yin Yang 1-associated protein 1.

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Citation: Gu YC, Li X, Zhao YJ, Wu T, Zhou CG, Hu WL, Fu ZW, Huang JH, Ren ZY. Yin Yang 1-associated protein 1: Clinical significance and underlying functional mechanisms in gastric cancer. World J Gastroenterol 2026; 32(21): 116527
URL: https://www.wjgnet.com/1007-9327/full/v32/i21/116527.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i21.116527

Gu YC, Li X, Zhao YJ, Wu T, Zhou CG, Hu WL, Fu ZW, Huang JH, Ren ZY. Yin Yang 1-associated protein 1: Clinical significance and underlying functional mechanisms in gastric cancer. World J Gastroenterol 2026; 32(21): 116527 [DOI: 10.3748/wjg.v32.i21.116527]

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