Salidroside mitigates experimental colitis through cyclic adenosine monophosphate pathway activation and suppression of enteric glial cell responses

doi:10.3748/wjg.v32.i21.116337

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 7, 2026; 32(21): 116337
Published online Jun 7, 2026. doi: 10.3748/wjg.v32.i21.116337

Table 2 Histological index score

Score	Degree of inflammation	Extent of inflammation	Crypt damage
0	None	None	None
1	Slight	Mucosa	Basal 2/3 damaged
2	Medium	Mucosa and submucosa	Basal 2/3 damaged
3	Severe	Muscular or transmural	Only surface epithelium intact
4	Severe	Muscular or transmural	Entire crypt and epithelium lost

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Citation: Li Y, Tao SS, Wang Y, Sun Q, Li MY, Zhang H, Li YQ. Salidroside mitigates experimental colitis through cyclic adenosine monophosphate pathway activation and suppression of enteric glial cell responses. World J Gastroenterol 2026; 32(21): 116337
URL: https://www.wjgnet.com/1007-9327/full/v32/i21/116337.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i21.116337

Li Y, Tao SS, Wang Y, Sun Q, Li MY, Zhang H, Li YQ. Salidroside mitigates experimental colitis through cyclic adenosine monophosphate pathway activation and suppression of enteric glial cell responses. World J Gastroenterol 2026; 32(21): 116337 [DOI: 10.3748/wjg.v32.i21.116337]

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