Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation

doi:10.3748/wjg.v32.i20.117044

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 32, Issue 20

This Article

(26)

(25)

(0)

(1)

(802)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. May 28, 2026; 32(20): 117044
Published online May 28, 2026. doi: 10.3748/wjg.v32.i20.117044

Full Size Figure Download Figure

Figure 2 Illustration of the coordinated control of parietal cell acid secretion by gastrin, somatostatin, and histamine. Gastrin stimulates enterochromaffin-like cells via CCK-2 receptors to release histamine, which activates parietal cells through H₂ receptors. Somatostatin from delta cells exerts inhibitory effects through SSTR2 on gastrin cells, ECL cells, and parietal cells, maintaining feedback regulation of gastric acid output.

Citation: Zheng HC, Zhou T, Sun L, Ding X. Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation. World J Gastroenterol 2026; 32(20): 117044
URL: https://www.wjgnet.com/1007-9327/full/v32/i20/117044.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i20.117044

Zheng HC, Zhou T, Sun L, Ding X. Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation. World J Gastroenterol 2026; 32(20): 117044 [DOI: 10.3748/wjg.v32.i20.117044]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.