Therapeutic effects of rhubarb enema on Th17 cell and systemic inflammatory response in clinical acute pancreatitis

doi:10.3748/wjg.v32.i20.116036

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World Journal of Gastroenterology

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1007-9327

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. May 28, 2026; 32(20): 116036
Published online May 28, 2026. doi: 10.3748/wjg.v32.i20.116036

Table 2 Correlation coefficients between Balthazar Computed Tomography Severity Index score and cytokines

	CTSI score	IL-6	IL-17A	TNF-α	IL-8	IL-1β	CXCL-1	Th17	IL-10
CTSI score		0.26 (P = 0.02)	0.30 (P < 0.01)	0.28 (P = 0.01)	0.42 (P < 0.01)	0.12 (P > 0.05)	0.06 (P > 0.05)	0.30 (P < 0.01)	-0.26 (P < 0.01)
IL-6			0.42 (P < 0.01)	0.06 (P > 0.05)	0.05 (P > 0.05)	0.07 (P > 0.05)	-0.11 (P > 0.05)	0.37 (P < 0.01)	-0.34 (P < 0.01)
IL-17A				0.53 (P < 0.01)	0.11 (P > 0.05)	0.27 (P < 0.01)	0.12 (P > 0.05)	0.71 (P < 0.01)	-0.52 (P < 0.01)
TNF-α					0.09 (P > 0.05)	0.16 (P > 0.05)	-0.03 (P > 0.05)	0.44 (P < 0.01)	-0.32 (P < 0.01)
IL-8						0.04 (P > 0.05)	0.02 (P > 0.05)	0.08 (P > 0.05)	-0.15 (P > 0.05)
IL-1β							0.39 (P < 0.01)	0.51 (P < 0.01)	-0.08 (P > 0.05)
CXCL-1								0.35 (P < 0.01)	-0.52 (P < 0.01)
Th17									-0.23 (P < 0.01)

CTSI: Balthazar Computed Tomography Severity Index; TNF-α: Tumor necrosis factor-alpha; IL: Interleukin.

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Citation: Zhong LG, Luo Y, Gao F, Guo TT, Yang J, Wang CJ. Therapeutic effects of rhubarb enema on Th17 cell and systemic inflammatory response in clinical acute pancreatitis. World J Gastroenterol 2026; 32(20): 116036
URL: https://www.wjgnet.com/1007-9327/full/v32/i20/116036.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i20.116036

Zhong LG, Luo Y, Gao F, Guo TT, Yang J, Wang CJ. Therapeutic effects of rhubarb enema on Th17 cell and systemic inflammatory response in clinical acute pancreatitis. World J Gastroenterol 2026; 32(20): 116036 [DOI: 10.3748/wjg.v32.i20.116036]

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