Cedrol ameliorates ulcerative colitis via myeloid differentiation factor 2-mediated inflammation suppression, with barrier restoration and microbiota modulation

Figure 7 Cedrol ameliorated dextran sulfate sodium-induced gut microbiota dysbiosis. A: Venn diagram of amplicon sequence variants for each group; B and C: Alpha diversity analysis (Shannon and Simpson indices); D and E: Beta diversity was displayed via principal coordinates analysis and non-metric multidimensional scaling based on weighted UniFrac algorithm; F: Phylum-level abundance distribution; G: Genus-level relative abundance; H: Differences in bacterial abundance were analyzed at the genus level across various groups (P < 0.05); I: Linear discriminate analysis effect size-derived linear discriminant analysis scores; J: Kyoto Encyclopedia of Genes and Genomes functional prediction heatmap. Data are expressed as mean ± SD (n = 4). CE: Cedrol; DSS: Dextran sulfate sodium; PCoA: Principal co-ordinates analysis; NMDS: Non-metric multidimensional scaling; LDA: Linear discriminate analysis; KEGG: Kyoto Encyclopedia of Genes and Genomes.