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Basic Study
©The Author(s) 2026.
World J Gastroenterol. Jan 14, 2026; 32(2): 114057
Published online Jan 14, 2026. doi: 10.3748/wjg.v32.i2.114057
Table 2 Histopathological scoring criteria
Score
Inflammation extent
Crypt damage
Ulceration
Edema
0NoneIntact crypt architectureNo ulcerAbsent
1Scattered submucosal cellsSome crypt damageSmall focal ulcersPresent
2Focal submucosal infiltratesIncreased crypt spacing, goblet cell loss, crypt shorteningFrequent small ulcers
3Focal submucosal, lamina propria infiltratesLarge crypt-deficient areas amid normal cryptsExtensive surface epithelial loss
4Extensive submucosal, lamina propria, perivascular infiltratesCrypt absence
5Transmural inflammation


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