Association of FADS2 polymorphism rs174538 with fatty acid metabolism and disease severity in Japanese patients with Crohn’s disease

doi:10.3748/wjg.v32.i2.112132

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2026; 32(2): 112132
Published online Jan 14, 2026. doi: 10.3748/wjg.v32.i2.112132

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Figure 4 Genes linked to rs174538, based on analysis of reports of genetic polymorphisms that result in high linoleic acid and low arachidonic acid. Analysis of polymorphisms and rs174538 in Japanese Multi Omics Reference Panel showed that most of the polymorphisms had linkage.

Citation: Matsuzawa H, Ito Z, Uchiyama K, Motoi Y, Ohtaki Y, Iwashita Y, Suzuki S, Nakada T, Koido S, Kojima K, Murohashi K, Saruta M, Ohkusa T, Kubota T. Association of FADS2 polymorphism rs174538 with fatty acid metabolism and disease severity in Japanese patients with Crohn’s disease. World J Gastroenterol 2026; 32(2): 112132
URL: https://www.wjgnet.com/1007-9327/full/v32/i2/112132.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i2.112132

Matsuzawa H, Ito Z, Uchiyama K, Motoi Y, Ohtaki Y, Iwashita Y, Suzuki S, Nakada T, Koido S, Kojima K, Murohashi K, Saruta M, Ohkusa T, Kubota T. Association of FADS2 polymorphism rs174538 with fatty acid metabolism and disease severity in Japanese patients with Crohn’s disease. World J Gastroenterol 2026; 32(2): 112132 [PMID: 41551830 DOI: 10.3748/wjg.v32.i2.112132]

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