Association of FADS2 polymorphism rs174538 with fatty acid metabolism and disease severity in Japanese patients with Crohn’s disease

Figure 2 Findings in relation to rs174538 mutation. A: For serum and erythrocyte membranes, and rd.d6di. ^bP < 0.05 for wild vs hetero; B: For serum and erythrocyte membranes, and d5di. ^cP < 0.05 for wild vs homo, ^dP < 0.0001 for wild vs homo, ^eP < 0.001 for wild vs hetero, ^fP < 0.05 for hetero vs homo; C: For serum and erythrocyte membranes, and arachidonic acid. ^gP < 0.001 for wild vs homo, ^hP < 0.001 for wild vs hetero, ⁱP < 0.05 for wild vs homo, ^jP < 0.01 for wild vs hetero. ¹ANOVA, followed by Tukey’s HSD test. Rrd.d6di: Red blood cell redefined δ6 desaturase index; Srd.d6di: Serum redefined δ6 desaturase index; rd5di: Red blood cell δ5 desaturase index; sd5di: Serum δ5 desaturase index; rAA: Red blood cell arachidonic acid; sAA: Serum arachidonic acid.