Branch duct intraductal papillary mucinous neoplasms: How ready are we to de-escalate surveillance?

doi:10.3748/wjg.v32.i19.115852

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. May 21, 2026; 32(19): 115852
Published online May 21, 2026. doi: 10.3748/wjg.v32.i19.115852

Table 2 Longitudinal profiles of physical and biochemical characteristics of cysts for each degree of dysplasia

		LGD	IGD	HGD	Malignant	Not stated	Imaged only	Total
Cyst size (mm)	< 30	33	10	0	7	9	825	884
	> 30	18	11	3	4	5	60	101
	Total	51	21	3	11	14	885	985
Missing		15	5	3	24	6	259	312
Cyst CEA (μg/L)	< 450	56	21	6	32	16	345	476
	> 450	8	4	0	0	0	5	17
	Total	64	25	6	32	16	350	493
Missing		2	1	0	3	4	794	804
Cyst CA19-9 (KU/L)	< 90	54	21	6	17	16	301	415
	> 90	10	4	0	15	0	49	78
	Total	64	25	6	32	16	350	493
Missing		2	1	0	3	4	794	804
Serum CEA (μg/L)	< 5	31	12	3	8	14	635	703
	> 5	2	0	0	0	1	18	21
	Total	33	12	3	8	15	653	724
Missing		33	14	3	27	5	491	573
Serum CA19-9 (KU/L)	< 40	56	22	5	10	15	678	786
	> 40	9	3	1	23	3	55	94
	Total	65	25	6	33	18	733	880
Missing		1	1	0	2	2	411	417

LGD: Low grade dysplasia; IGD: Intermediate grade dysplasia; HGD: High grade dysplasia; CEA: Carcinoembryonic antigen; CA19-9: Cancer antigen 19-9.

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Citation: Hopley PJ, Whelan P, Jackson R, Evans J, Andrews T, Ghaneh P, Raraty M, Greenhalf W, Halloran CM. Branch duct intraductal papillary mucinous neoplasms: How ready are we to de-escalate surveillance? World J Gastroenterol 2026; 32(19): 115852
URL: https://www.wjgnet.com/1007-9327/full/v32/i19/115852.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i19.115852

Hopley PJ, Whelan P, Jackson R, Evans J, Andrews T, Ghaneh P, Raraty M, Greenhalf W, Halloran CM. Branch duct intraductal papillary mucinous neoplasms: How ready are we to de-escalate surveillance? World J Gastroenterol 2026; 32(19): 115852 [DOI: 10.3748/wjg.v32.i19.115852]

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