Predictive value of neutrophil-lymphocyte ratio for prognosis in patients with advanced hepatocellular carcinoma treated with programmed cell death 1 inhibitors

doi:10.3748/wjg.v32.i18.118416

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. May 14, 2026; 32(18): 118416
Published online May 14, 2026. doi: 10.3748/wjg.v32.i18.118416

Table 8 Multivariate logistic regression analysis of factors influencing objective response rate

Variable	Coefficient	SE	Wald stat	P value	OR	OR CI lower	OR CI upper
NLR (high vs low)	-1.045	0.336	-3.112	0.002	0.352	0.182	0.680
BCLC stage (C vs B)	-0.222	0.369	-0.602	0.552	0.801	0.387	1.656
Maximum tumor diameter (cm)	-0.132	0.080	-1.649	0.102	0.877	0.749	1.027
Macrovascular invasion (yes vs no)	-0.068	0.332	-0.206	0.838	0.934	0.483	1.805
Extrahepatic spread (yes vs no)	-0.327	0.340	-0.963	0.334	0.721	0.371	1.402

NLR: Neutrophil-to-lymphocyte ratio; BCLC: Barcelona Clinic Liver Cancer; OR: Odds ratio; CI: Confidence interval.

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Citation: Guo R, Gao M. Predictive value of neutrophil-lymphocyte ratio for prognosis in patients with advanced hepatocellular carcinoma treated with programmed cell death 1 inhibitors. World J Gastroenterol 2026; 32(18): 118416
URL: https://www.wjgnet.com/1007-9327/full/v32/i18/118416.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i18.118416