Predictive value of neutrophil-lymphocyte ratio for prognosis in patients with advanced hepatocellular carcinoma treated with programmed cell death 1 inhibitors

Table 6 Comparison of hematological parameters between patients with low neutrophil-to-lymphocyte ratio and high neutrophil-to-lymphocyte ratio

Variable	Low NLR group (n = 129)	High NLR group (n = 105)	t	P value
AFP (ng/mL)	568.35 ± 125.63	783.27 ± 182.29	10.26	< 0.001
ALT (U/L)	45.92 ± 10.45	48.08 ± 11.32	1.516	0.131
AST (U/L)	49.98 ± 12.25	54.78 ± 13.82	2.812	0.005
Total bilirubin (μmol/L)	18.95 ± 4.25	20.74 ± 4.95	2.983	0.003
Albumin (g/L)	38.34 ± 3.79	36.77 ± 3.97	3.099	0.002
International normalized ratio	1.10 ± 0.27	1.22 ± 0.28	3.472	< 0.001
Blood urea nitrogen (mmol/L)	5.25 ± 1.11	5.51 ± 1.27	1.687	0.093
Serum creatinine (μmol/L)	78.49 ± 15.31	81.32 ± 16.54	1.357	0.176

NLR: Neutrophil-to-lymphocyte ratio; AFP: Alpha fetoprotein; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.