Letter to the Editor: Leucine-rich α-2-glycoprotein in Taiwanese inflammatory bowel disease: Strengths and limitations of a novel serum marker

Figure 2 Summary of biomarker performance for predicting endoscopic activity in ulcerative colitis and Crohn’s disease. Comparative visualization of the area under the curve values for C-reactive protein (CRP), leucine-rich alpha-2 glycoprotein (LRG), and fecal calprotectin is shown. Additionally, it includes the composite model combining CRP, hemoglobin, and LRG in ulcerative colitis patients with low or normal CRP. It illustrates that LRG provides modest standalone discrimination but improves diagnostic accuracy when used in serum-based composite panels. UC: Ulcerative colitis; CD: Crohn’s disease; LGR: Leucine-rich alpha-2 glycoprotein; CRP: C-reactive protein; FC: Fecal calprotectin; AUC: Area under the curve; Hb: Hemoglobin.