LGALS1 drives chemoresistance in esophageal squamous cell carcinoma by modulating epithelial-mesenchymal transition and tumor immunity

Figure 1 Comprehensive analysis of single-cell subpopulations in esophageal squamous cell carcinoma patients receiving neoadjuvant chemoradiotherapy and surgical treatment. A: UMAP visualization of 43407 high-quality cells across all 7 cellular types; B: Marker genes for distinct cell types, with coloring based on Z-score normalized expression levels; C: UMAP visualization of all cells derived from normal tissue, surgical and neoadjuvant chemoradiotherapy groups; D: UMAP visualization of all cells obtained from 8 samples; E: Distribution and quantities of distinct cell types across 8 specimens; F: Distribution and quantities of distinct cell types within the 3 groups. NeoCRT: Neoadjuvant chemoradiotherapy; NK: Natural killer.