Impact of rebleeding after transjugular intrahepatic portosystemic shunt on liver-related death based on liver function categories

doi:10.3748/wjg.v32.i17.116867

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. May 7, 2026; 32(17): 116867
Published online May 7, 2026. doi: 10.3748/wjg.v32.i17.116867

Table 3 Univariable and multivariable analysis of liver-related deaths in patients undergoing transjugular intrahepatic portosystemic shunt

Variable	Univariate analysis		Multivariate analysis
Variable	HR (95%CI)	P value	HR (95%CI)	P value
Age	1.030 (1.020-1.040)	< 0.001	1.031 (1.022-1.040)	< 0.001
Sex (female vs male)	1.080 (0.889-1.320)	0.424
Cirrhosis etiology
Alcoholic liver disease vs chronic HBV infection	0.832 (0.509-1.360)	0.107
Other viral infection vs chronic HBV infection	1.330 (0.938-1.900)	0.109
Autoimmune hepatitis vs chronic HBV infection	1.100 (0.768-1.570)	0.603
Mixed etiology vs chronic HBV infection	0.960 (0.475-1.940)	0.107
Others vs chronic HBV infection	1.210 (0.929-1.580)	0.156
Previous ascites
Mild vs no	1.260 (0.996-1.600)	0.054
Moderate and severe vs no	2.070 (1.630-2.630)	< 0.001
Child-Pugh score	1.260 (1.200-1.330)	< 0.001	1.207 (1.121-1.300)	< 0.001
Model for end-stage liver disease-Na score	1.060 (1.040-1.070)	< 0.001	1.035 (1.016-1.055)	< 0.001
Transjugular intrahepatic portosystemic shunt stent diameter
8 mm vs < 8 mm	0.912 (0.484-1.720)	0.775
10 mm vs < 8 mm	1.240 (0.615-2.490)	0.549
Portal pressure gradient reduction	1.010 (0.997-1.030)	0.119
Rebleeding	1.490 (1.210-1.840)	< 0.001	1.609 (1.304-1.986)	< 0.001

HR: Hazard ratio; CI: Confidence interval.

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Citation: Zhu JY, Tie J, Xia YF, Wang GC, Zhuge YZ, Wu H, Zhu XL, Xue H, Xu J, Zhang F, Zhao LH, Huang GJ, Zhang MY, Li Z, Wei B, Li PJ, Wang Z, Wu W, Chen C, Tang CW, Zhang CQ. Impact of rebleeding after transjugular intrahepatic portosystemic shunt on liver-related death based on liver function categories. World J Gastroenterol 2026; 32(17): 116867
URL: https://www.wjgnet.com/1007-9327/full/v32/i17/116867.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i17.116867

Zhu JY, Tie J, Xia YF, Wang GC, Zhuge YZ, Wu H, Zhu XL, Xue H, Xu J, Zhang F, Zhao LH, Huang GJ, Zhang MY, Li Z, Wei B, Li PJ, Wang Z, Wu W, Chen C, Tang CW, Zhang CQ. Impact of rebleeding after transjugular intrahepatic portosystemic shunt on liver-related death based on liver function categories. World J Gastroenterol 2026; 32(17): 116867 [DOI: 10.3748/wjg.v32.i17.116867]

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