Niu Huang mitigates dextran sulfate sodium-induced colitis by modulating farnesoid X receptor activation and the complement 3/NLRP3 signaling pathway

Figure 6 Integrated analysis of transcriptomics and proteomics. A: The differentially expressed genes showed differences at both the RNA and protein levels; B: Interaction network of the differentially expressed genes; C: The Kyoto Encyclopedia of Genes and Genomes pathways upregulated in the dextran sulfate sodium (DSS) group relative to the control group and downregulated in the Niu Huang group relative to the DSS group at both the RNA and protein levels; D: Gene set enrichment analysis showed that bile secretion was downregulated in the DSS group and upregulated after Niu Huang treatment at both the RNA and protein levels. DSS: Dextran sulfate sodium; NH: Niu Huang.