Niu Huang mitigates dextran sulfate sodium-induced colitis by modulating farnesoid X receptor activation and the complement 3/NLRP3 signaling pathway

Figure 1 Network pharmacology analysis of Niu Huang in alleviating ulcerative colitis. A: Venn diagram of Niu Huang in regulating ulcerative colitis; B: Ingredient-target network. The yellow rhombus represents the components of Niu Huang, and the blue nodes represent the core targets; C: Protein-protein interaction network of the core genes. The intensity of the color represents the degree of significance; D: The top 10 biological process, cellular component and molecular function of Gene Ontology enrichment analysis; E: The top 20 pathways of Kyoto Encyclopedia of Genes and Genomes pathways analysis; F: Component-target network for complement and coagulation cascades. NH: Niu Huang; UC: Ulcerative colitis; BP: Biological process; CC: Cellular component; MF: Molecular function.