Plasma proteomic profiling of gastric cancer: Super minimally invasive surgery vs organ-resection on trauma immunity

doi:10.3748/wjg.v32.i16.117799

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 28, 2026; 32(16): 117799
Published online Apr 28, 2026. doi: 10.3748/wjg.v32.i16.117799

Table 1 Comparison of general data of gastric cancer patients in two groups, n (%)/median (interquartile range)/mean ± SD

Variables	SMIS (n = 20)	ORS (n = 18)	P value
Gender			0.164
Male	18 (90)	13 (72)
Female	2 (10)	5 (28)
Age (years)	61 (55.5, 72)	60.5 (46.5 65)	0.219
BMI (kg/m²)	24.95 (23.6, 27.25)	22.95 (21.15, 26.05)	0.106
Smoking history	7 (35)	7 (39)	1.000
History of alcohol use	10 (50)	9 (50)	1.000
History of Helicobacter pylori infection	3 (15)	3 (17)	1.000
Hypertension	10 (50)	6 (33)	0.342
Diabetes	5 (25)	4 (22)	1.000
Coronary heart disease, pre-operative blood test	4 (20)	1 (6)	0.344
White blood cells (× 10⁹/L)	6.085 (5.515, 7.57)	5.57 (4.385, 7.185)	0.148
Neutrophils (× 10⁹/L)	0.558 ± 0.721	0.608 ± 0.949	0.076
Lymphocytes (× 10⁹/L)	0.335 ± 0.729	0.293 ± 0.853	0.12
Monocytes (× 10⁹/L)	0.0775 (0.065, 0.088)	0.074 (0.057, 0.082)	0.342
Previous medication history			1.000
Anti-inflammatory drugs (anticoagulants, anti-platelet drugs, non-steroidal anti-inflammatory drugs, hormonal drugs)	2 (10)	1 (5.6)
No anti-inflammatory medication	18 (90)	17 (94.4)

SMIS: Super minimally invasive surgery; ORS: Organ-resection surgery; BMI: Body mass index.

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Citation: Yuan YQ, Chen QQ, Xiao P, Li HK, Lv KM, Tian S, Shi H, Hao J, Yan Y, Linghu EQ. Plasma proteomic profiling of gastric cancer: Super minimally invasive surgery vs organ-resection on trauma immunity. World J Gastroenterol 2026; 32(16): 117799
URL: https://www.wjgnet.com/1007-9327/full/v32/i16/117799.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i16.117799

Yuan YQ, Chen QQ, Xiao P, Li HK, Lv KM, Tian S, Shi H, Hao J, Yan Y, Linghu EQ. Plasma proteomic profiling of gastric cancer: Super minimally invasive surgery vs organ-resection on trauma immunity. World J Gastroenterol 2026; 32(16): 117799 [DOI: 10.3748/wjg.v32.i16.117799]

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