Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort

Table 8 Multivariable logistic regression analysis of risk factors for low anterior resection syndrome at 12 months postoperatively

	β	SE	Wald χ2	df	P value	Exp(B)	95%CI for Exp(B)
							Lower	Upper
Tumor location (> 3 cm)	1.077	0.425	6.41	1	0.011	2.935	1.275	6.756
Gender (female)	-0.038	0.368	0.011	1	0.918	0.963	0.468	1.981
Age (< 61.28 years)	0.004	0.38	0	1	0.992	1.004	0.476	2.115
Blood type (A)			5.134	3	0.162
AB	-0.934	0.52	3.222	1	0.073	0.393	0.142	1.09
B	0.616	0.638	0.933	1	0.334	1.851	0.53	6.459
O	-0.173	0.405	0.182	1	0.669	0.841	0.38	1.861
BMI (< 23.42 kg/m2)	-0.27	0.365	0.548	1	0.459	0.763	0.373	1.56
Diabetes (no)	0.466	0.449	1.081	1	0.299	1.594	0.662	3.841
Hypertension (no)	-0.438	0.396	1.226	1	0.268	0.645	0.297	1.401
Tumor pathology (adenocarcinoma)			1.239	3	0.744
Neuroendocrine carcinoma	-21.555	40192.97	0	1	1	0	0
Signet ring cell carcinoma	-19.393	28190.679	0	1	0.999	0	0
Mucinous adenocarcinoma	-0.73	0.655	1.239	1	0.266	0.482	0.133	1.742
TNM (0)			2.71	4	0.608
I	0.611	0.614	0.992	1	0.319	1.843	0.553	6.135
II	0.573	0.642	0.797	1	0.372	1.773	0.504	6.239
III	-0.157	0.739	0.045	1	0.832	0.855	0.201	3.635
IV	0.105	0.801	0.017	1	0.895	1.111	0.231	5.344
Postoperative complications (no)	-0.098	0.877	0.012	1	0.911	0.907	0.162	5.061
Neoadjuvant chemotherapy (no)	-0.35	0.518	0.458	1	0.499	0.705	0.255	1.943
Neoadjuvant radiotherapy (no)	0.494	0.503	0.964	1	0.326	1.638	0.611	4.39
Constant	-1.162	0.951	1.493	1	0.222	0.313

Age and body mass index were converted into binary variables using the mean as the cutoff. Reference categories are shown in parentheses. BMI: Body mass index.