Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort

Table 6 Multivariable logistic regression analysis of risk factors for low anterior resection syndrome at 6 months postoperatively

	β	SE	Wald χ2	df	P value	Exp(B)	95%CI for Exp(B)
							Lower	Upper
Tumor location (> 3 cm)	0.953	0.363	6.896	1	0.009	2.594	1.273	5.284
Gender (female)	-0.161	0.319	0.255	1	0.614	0.851	0.455	1.592
Age (< 61.28 years)	-0.097	0.323	0.09	1	0.764	0.908	0.482	1.71
Blood type (A)			2.487	3	0.478
AB	-0.118	0.409	0.083	1	0.773	0.889	0.399	1.981
B	0.891	0.623	2.048	1	0.152	2.438	0.719	8.264
O	0.114	0.357	0.102	1	0.749	1.121	0.557	2.257
BMI (< 23.42 kg/m2)	-0.194	0.313	0.384	1	0.535	0.824	0.447	1.52
Diabetes (no)	0.134	0.394	0.115	1	0.734	1.143	0.528	2.472
Hypertension (no)	-0.767	0.345	4.952	1	0.026	0.464	0.236	0.913
Tumor pathology (adenocarcinoma)			0.002	3	1
Neuroendocrine carcinoma	-21.827	40192.97	0	1	1	0	0
Signet ring cell carcinoma	-19.705	26717.346	0	1	0.999	0	0
Mucinous adenocarcinoma	-0.027	0.604	0.002	1	0.965	0.974	0.298	3.183
TNM (0)			2.583	4	0.63
I	0.042	0.5	0.007	1	0.933	1.043	0.391	2.779
II	-0.224	0.526	0.182	1	0.67	0.799	0.285	2.242
III	-0.285	0.598	0.228	1	0.633	0.752	0.233	2.426
IV	-0.88	0.683	1.66	1	0.198	0.415	0.109	1.582
Postoperative complications (no)	-0.351	0.759	0.213	1	0.644	0.704	0.159	3.118
Neoadjuvant chemotherapy (no)	-0.013	0.444	0.001	1	0.977	0.987	0.414	2.356
Neoadjuvant radiotherapy (no)	0.427	0.433	0.974	1	0.324	1.533	0.656	3.582
Constant	-0.485	0.822	0.348	1	0.555	0.616

Age and body mass index were converted into binary variables using the mean as the cutoff. Reference categories are shown in parentheses. BMI: Body mass index.