Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort

Table 5 Multivariable logistic regression analysis of risk factors for low anterior resection syndrome at 3 months postoperatively

	β	SE	Wald χ2	df	P value	Exp(B)	95%CI for Exp(B)
							Lower	Upper
Tumor location (> 3 cm)	1.166	0.362	10.398	1	0.001	3.21	1.58	6.52
Gender (female)	0.425	0.317	1.799	1	0.18	1.529	0.822	2.843
Age (< 61.28 years)	-0.217	0.323	0.451	1	0.502	0.805	0.427	1.516
Blood type (A)			1.618	3	0.655
AB	-0.251	0.402	0.389	1	0.533	0.778	0.354	1.712
B	-0.476	0.614	0.601	1	0.438	0.621	0.187	2.069
O	-0.424	0.356	1.416	1	0.234	0.654	0.326	1.316
BMI (< 23.42 kg/m2)	0.078	0.309	0.064	1	0.801	1.081	0.59	1.98
Diabetes (no)	0.214	0.386	0.308	1	0.579	1.239	0.582	2.637
Hypertension (no)	-0.309	0.334	0.858	1	0.354	0.734	0.382	1.412
Tumor pathology (adenocarcinoma)			0.357	3	0.949
Neuroendocrine carcinoma	-21.921	40192.97	0	1	1	0	0
Signet ring cell carcinoma	0.172	1.63	0.011	1	0.916	1.188	0.049	29.01
Mucinous adenocarcinoma	-0.324	0.611	0.282	1	0.595	0.723	0.218	2.393
TNM (0)			8.403	4	0.078
I	0.003	0.507	0	1	0.995	1.003	0.371	2.71
II	-0.522	0.534	0.954	1	0.329	0.594	0.208	1.691
III	-1.18	0.614	3.698	1	0.054	0.307	0.092	1.023
IV	-1.258	0.673	3.495	1	0.062	0.284	0.076	1.063
Postoperative complications (no)	-0.427	0.71	0.361	1	0.548	0.653	0.162	2.625
Neoadjuvant chemotherapy (no)	0.572	0.432	1.753	1	0.185	1.772	0.76	4.131
Neoadjuvant radiotherapy (no)	-0.407	0.435	0.873	1	0.35	0.666	0.284	1.562
Constant	-0.027	0.825	0.001	1	0.974	0.973

Age and body mass index were converted into binary variables using the mean as the cutoff. Reference categories are shown in parentheses. BMI: Body mass index.