Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort

doi:10.3748/wjg.v32.i16.116405

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 28, 2026; 32(16): 116405
Published online Apr 28, 2026. doi: 10.3748/wjg.v32.i16.116405

Table 2 Comparison of baseline characteristics in the matched cohort (n = 220), n (%)

Characteristic	n	Ultra-low group (≤ 3 cm; n = 110)	Non-ultra-low group (> 3 cm; n = 110)	Test statistic	P value
Age (year)	220	58.08 ± 10.978	64.47 ± 11.242	t = 4.266	0.576
Gender
Female	95	41 (37.3)	54 (49.1)	χ² = 3.131	0.077
Male	125	69 (62.7)	56 (50.9)
BMI (kg/m²)		23.75 ± 3.14	23.23 ± 2.99	t = -1.259	0.933
Blood type
A	74	37 (33.6)	37 (33.6)	χ² = 1.530	0.675
AB	16	10 (9.1)	6 (5.5)
B	50	26 (23.6)	24 (21.8)
O	80	37 (33.6)	43 (39.1)
Diabetes
No	176	91 (82.7)	85 (77.3)	χ² = 1.023	0.312
Yes	44	19 (17.3)	25 (22.7)
Hypertension
No	150	76 (69.1)	74 (67.3)	χ² = 0.084	0.772
Yes	70	34 (30.9)	36 (32.7)
Tumor pathology
Adenocarcinoma	202	97 (88.2)	105 (95.5)	χ² = 4.583	0.205
Mucinous adenocarcinoma	15	11 (10.0)	4 (3.6)
Neuroendocrine carcinoma	1	1 (0.9)	0 (0.0)
Signet ring cell carcinoma	2	1 (0.9)	1 (0.9)
TNM
0	27	13 (11.8)	14 (12.7)	χ² = 25.940	< 0.001
I	82	32 (29.1)	50 (45.5)
II	57	22 (20.0)	35 (31.8)
III	33	26 (23.6)	7 (6.4)
IV	21	17 (15.5)	4 (3.6)
Postoperative complications
No	210	106 (96.4)	104 (94.5)	χ² = 0.419	0.517
Yes	10	4 (3.6)	6 (5.5)
Neoadjuvant radiotherapy
No	136	46 (41.8)	90 (81.8)	χ² = 37.283	< 0.001
Yes	84	64 (58.2)	20 (18.2)
Neoadjuvant chemotherapy
No	102	26 (23.6)	76 (69.1)	χ² = 45.696	< 0.001
Yes	118	84 (76.4)	34 (30.9)

BMI: Body mass index.

Full Size Table

Citation: Wang HS, Lin YX, Xu SR, Wang LY, Wang XD, Huang MJ. Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort. World J Gastroenterol 2026; 32(16): 116405
URL: https://www.wjgnet.com/1007-9327/full/v32/i16/116405.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i16.116405

Wang HS, Lin YX, Xu SR, Wang LY, Wang XD, Huang MJ. Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort. World J Gastroenterol 2026; 32(16): 116405 [DOI: 10.3748/wjg.v32.i16.116405]

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