Habitat imaging on contrast-enhanced magnetic resonance imaging predicts early response to transarterial chemoembolization in hepatocellular carcinoma

Figure 4 Decision curve analysis of the seven models in the internal training set, internal validation set, and external validation set. This figure presents the decision curve analysis results of the seven models across three cohorts. A: Internal training set; B: Internal validation set; C: External validation set. As shown in the figure, the combined model, integrating clinical variables, traditional radiomics features, and the intratumoral heterogeneity index, achieves significantly higher net benefits than other single models or pairwise combined models within a wide range of threshold probability intervals in all three panels. This indicates that the combined model has good guiding value for clinical decision-making. ITH: Intratumoral heterogeneity.